1991;4(2):166-173. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. View abstract. Mamgain RK, Gupta M, Mamgain P, et al. Anonymous. Robles BJ, Sandoval AR, Dardon JD, Blas CA. View abstract. View abstract. View abstract. View abstract. Peony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. It might also decrease the effects of birth control pills. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. View abstract. Licorice has anti-acid and relieves the tension of gastrointestinal smooth muscle. View abstract. View abstract. View abstract. View abstract. 1991;78(1-2):1-6. Zhang W, Dai SM. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. View abstract. J Altern Complement Med. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Pfeifer BL, Pirani JF, Hamann SR, Klippel KF. Researchers from the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial. The sweet cake that reaches parts other cakes can't! View abstract. Phytother Res. View abstract. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. View abstract. J Assoc Physicians India 1989;37(10):647. Medicinal herbs: modulation of estrogen action. Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. View abstract. Am J Psychiatry 1994;151:617-8. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. Qi XG. Fung AY, Look PC, Chong LY, et al. Title 21. View abstract. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. But I didn't take it long enough to see any change. Eagon PK, Elm MS, Hunter DS, et al. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. All rights reserved. View abstract. Arch Pharm Res 2002;25(3):293-299. Akbari N, Asadimehr N, Kiani Z. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. There is only one reminder that peony tea contains caffeine. View abstract. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Peony might have some of the same effects as estrogen. The herb licorice may lower warfarin levels and can add to digoxin's effects. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. View abstract. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. 2000;20(3):173-175. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Hsu, Y. L., Wu, L. Y., Hou, M. F., Tsai, E. M., Lee, J. N., Liang, H. L., Jong, Y. J., Hung, C. H., and Kuo, P. L. Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Taking licorice along with "water pills" might make potassium levels drop too low. View abstract. B., and Zhang, Z. J. Au, T. K., Lam, T. L., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Yoshino T, Yanagawa T, Watanabe K. Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature review. View abstract. Biol Pharm Bull. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Menopause 2002;9:145-50. Sigurjonsdottir HA, Franzson L, Manhem K, et al. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. PC-SPES, a dietary supplement for the treatment of hormone-refractory prostate cancer. Biol Pharm Bull. Am J Chin Med 2003;31:445-53. . Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. View abstract. Li G, Simmler C, Chen L, et al. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Melzer J, Rosch W, Reichling J, et al. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. In 1977, researchers reported the case of a 58-year-old woman who was eating a whopping 1.8 kilograms (about 63.5 ounces) of black licorice per week and went into cardiac arrest. View abstract. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. The treatment of human cancer with agents prepared from bovine cartilage. Phytomedicine 2003;10:271-85. J Biol Response Mod 1985;4:551-84. Cancer Lett 12-10-2001;174(1):17-24. One of its most known effects is the induction of hypertension, and it can induce what appears to be pseudohyperaldosteronism, due to glycyrrhetinic acid, the main active component of the root. View abstract. Chinese peony root comes in two different forms. The efficacy and safety of the combination of total glucosides of peony and leflunomide for the treatment of rheumatoid arthritis: a systematic review and meta-analysis. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. 1988;8(11):660-2, 645. A., Motallebnejad, M., and Khanian, M. The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. View abstract. View abstract. Am.J Chin Med 2004;32(4):569-578. Licorice seems to change hormone levels in the body. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. Med Princ Pract 2010;19(6):485-489. Clin Ter 1990;132(1):55-58. Man SC, Li XB, Wang HH, et al. Burgess, J. Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. Zong, P. P., Yan, T. Y., and Gong, M. M. [Clinical and experimental studies of effects of huayu decoction on scavenging free radicals]. . View abstract. View abstract. 17. View abstract. Side effects, toxicity, and interactions. Chang GH, Lin YS, Hsu KH, et al. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. Clin Pharmacol Ther 1996;59:62-71. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. J Clin Psychopharmacol 2016;36(6):572-9. View abstract. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. 1987;(10):46-48. Blood Press 2009;18:192-5. View abstract. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. Life Sci 9-27-2002;71(19):2267-2277. View abstract. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. 2004;4(3):377-386. One major reported side effect of licorice root is reduced levels of testosterone in men ( 10 ). View abstract. Clin Med (Lond) 2017;17(1):43-5. Back to the Blog. Qraa Advanced Lacto Dark Underarm Whitening Cream Product Claims Qraa underarm whitening cream claims to lighten dark underarms by reducing melanin from the skin in the area. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. View abstract. View abstract. View abstract. View abstract. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1090-1092. Zhang YD, Lorenzo B, Reidenberg MM. View abstract. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. View abstract. Braz J Infect Dis 2016;20(6):534-8. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. Licorice that has had this substance removed (called DGL for deglycyrrhizinated licorice) may not have the same degree of side effects. Some birth control pills contain estrogen. View abstract. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. 2011;25(2):312-313. J Am Coll.Nutr 2007;26(3):209-218. Effect of licorice on reduction of body fat mass in healthy subjects. J Dermatolog Treat 2003;14(3):153-157. View abstract. J Ethnopharmacol 2004;94:339-44. . Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. But the potential side effects are real enough. Celery juice has become very popular now as it is believed to cure many health problems including obesity, thyroid, gout, blood pressure and fluid retention. Am J Med Sci 2003;325:153-6. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . Abe Y, Ueda T, Kato T, Kohli Y. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. The author has contributed to research in topic(s): Rheum officinale. Motherwort, Peony, Dong Quai, Lady's Mantle, Licorice, and Rose, Fennel, Alfalfa. Hum Exp Toxicol 2012;31(12):1295-1298. Effect of shakuyaku-kanzoh-toh, a prescription composed of shakuyaku (Paeoniae Radix) and kanzoh (Glycyrrhizae Radix) on guinea pig ileum. View abstract. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. View abstract. Neurology 2010;75(21):1939-1941. Schleimer, R. P. Potential regulation of inflammation in the lung by local metabolism of hydrocortisone. Liu J. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. Dellow EL, Unwin RJ, Honour JW. 44 ($0.09/Count) NEW PACKAGING White Peony Root Bai Shao 4oz 38. . J Steroid Biochem Mol Biol 1994;49:81-5. Peony (Paeonia spp). View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Hawrelak, J. [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. It may disrupt the production of sex hormones ( 9 ). Agarwal, A., Gupta, D., Yadav, G., Goyal, P., Singh, P. K., and Singh, U. Evid Based Complement Alternat Med 2016;2016:9852793. Alt Med Rev 2001;6:495-9. View abstract. Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. View abstract. View abstract. However, taking too much licorice root may cause side effects. View abstract. Pak J Med Sci 2022;38(1):271-275. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Lancet 1990;335(8697):1060-3. Bisogni V, Rossi GP, Cal LA. Ann Pharmacother 2003;37(6):836-838. van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. View abstract. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Iran J Pharm Res. View abstract. View abstract. Peony might change how quickly the liver breaks down these medications. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. View abstract. View abstract. Madisch A, Holtmann G, Mayr G, et al. Quinkler M, Stewart PM. View abstract. Lancet 2000;355(9198):134-138. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. Biomed.Chromatogr. Tsuda T, Sugaya A, Ohguchi H, et al. 1999;15:499-523. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. However, when Angelica Sinensis was tested in combination with products containing other substances, its activity was reduced. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. View abstract. Complement Ther Med. View abstract. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. View abstract. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. Wu G, Wu N, Li T, et al. Neth J Med 2005;63:119-20. View abstract. View abstract. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. View abstract. (Tokyo) 2008;54(3):244-249. Guo TL, Zhou XW. Das SK, Das V, Gulati AK, and et al. B. and Tang, T. Q. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. View abstract. Neth J Med 2005;63:146-8. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin; Clopidogrel; Warfarin; St. John's wort. Ultrastruct Pathol 1992;16(5):529-535. What are the side-effects of taking liquorice? View abstract. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. Fitoterapia 2006;77(7-8):613-614. Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Case Rep Emerg Med. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. View abstract. 1991;11(4):199-202, 195. View abstract. Farese RV Jr, Biglieri EG, Shackleton CH, et al. J Altern Complement Med 2010;16(10):1065-1071. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. World J Gastroenterol 2005;11:2124-9. . View abstract. Intern Med 2017;56(2):175-9. Am J Epidemiol 2001;153:1085-8. View abstract. Licorice has been used as a medicinal plant from 2.500 years. Bernardi, M., D'Intino, P. E., Trevisani, F., Cantelli-Forti, G., Raggi, M. A., Turchetto, E., and Gasbarrini, G. Effects of prolonged ingestion of graded doses of licorice by healthy volunteers. Treatment of functional dyspepsia with a herbal preparation. Note: Results may vary from person to person, depending on the skin type. Contact Dermatitis 1999;40(1):56. View abstract. Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. Liapina LA, Ammosova IaM, Novikov VS, et al. View abstract. 5-10-2004;208(1):89-94. View abstract. Int Immunopharmacol. Pseudohyperaldosteronism, liquorice, and hypertension. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. View abstract. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress. Exp Clin Endocrinol Diabetes 2003;111:341-3. View abstract. Pharm Biol 2021;59(1):1276-1285. Lapi F, Gallo E, Bernasconi S, et al. WebMD does not provide medical advice, diagnosis or treatment. Amato P, Christophe S, Mellon PL. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. View abstract. Postgrad Med J 1980;56(657):526-529. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Br J Clin Pharmacol 2008;66:572-4. J Agric Food Chem 6-13-2007;55(12):4691-4697. View abstract. View abstract. Clin Neurol Neurosurg 1993;95(1):35-37. Li C, Wang ZB. Birth outcome in relation to licorice consumption during pregnancy. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. View abstract. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. View abstract. Loop diuretics can also decrease potassium levels. For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Phytother.Res 2004;18(3):241-243. Russo S, Mastropasqua M, Mosetti MA, et al. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Madisch A, Melderis H, Mayr G, et al. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. Jafari Z, Emtiazy M, Sohrabvand F, et al. Izv Akad Nauk Ser Biol 1997;2:235-7. . J Cosmet.Sci 2006;57(1):57-64. 1993;13(10):591-3, 579. View abstract. Z Gastroenterol 2001;39(7):511-7. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. A double-blind, randomized, placebo-controlled, multicenter trial. Low potassium levels can increase the side effects of digoxin. Int J Cardiol 2008;124(3):e42-e44. Eur J Drug Metab Pharmacokinet. View abstract. View abstract. View abstract. That's because licorice real black licorice, not the phony licorice-flavored stuff flavored with anise oil . Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. View abstract. 2007;30(10):1898-1904. Taking licorice with paclitaxel might decrease the effects of paclitaxel. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. View abstract. Medicine (Baltimore) 2019;98(35):e16601. Ha Y, Wang T, Li J, et al. Diane Calello, executive medical director of the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, discusses safe . A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Phytother Res 2008;22(6):709-724. Fatal hypokalaemic alkalosis with tetany during liquorice and P.A.S. N Engl J Med 1991;325:1223-7. View abstract. Wang H, Dong L, Qu F, et al. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. J Telemed Telecare. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. Antiviral Res 1987;7(2):99-107. Kimura Y, Okuda H, Okuda T, and et al. View abstract. American Herbal Products Association's Botanical Safety Handbook, Second Edition. View abstract. 2013 Jun;22(2):173-8. View abstract. Isr J Dent Sci 1989;2(3):153-157. 2013 Jun;19(4):227-8. View abstract. View abstract. 2017 Sep;31(9):1330-1340. Licorice might decrease the effects of warfarin. Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. J Hum Hypertens 2001;15:549-52. Koo YK, Kim JM, Koo JY, et al. J Gastroenterol Hepatol 1999;14(11):1093-1099. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. Gupta D, Agrawal S, Sharma JP. View abstract.