Her allergies have reared their ugly heads again - no jowl pyoderma, but ears itching. She is a New-York-based freelance author with a passion for equine health and veterinary care. Acupuncture: It appears that some horses with Equine Asthma can benefit from acupuncture to help with breathing function. Avoiding Allergies Avoid storing hay in the same barn as sensitive horses, since hay particles and spores can be irritating, even from a distance and even if they are not visible in the air. Dosage and administration For oral use. This drug has been used in dogs with some pretty fabulous results. Apoquel. Levy BJ, Linder KE, Olivry T. The role of oclacitinib in the management of ischaemic dermatopathy in four dogs. This content is intended for counseling purposes only. Speak to yourveterinarian in an emergency. Vet Dermatol 2016;27(1):22-e7. Vet Dermatol 2013;24(5):479-e114. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label. Apoquel. Fortunately, these side effects are relatively uncommon. 11. Your Price: $2.20. When your dog (cat, horse, child) reacts violently to everyday things like; flea saliva (even from one solitary flea) . But you're making a deal with the devil when you use these . Since some horses have both "types" of asthma, you may need to try a stall without bedding, or experiment with different types of bedding. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label.30. Cochet Faivre N, Degorce-Rubiales F. Clinical eosinophilic popular dermatitis associated with histological eosinophilic granuloma rapidly responsive to oclacitinib in an adult Labrador retriever. Renal Anemia, or . Shes on 5 pills once a day for 7 days, after that we will drop to every other day, and then see how far we can space it out. Because its essentially impossible to predict these events, its important to keep records of your horses previous reactions and communicate them to your veterinarian. APOQUEL may be administered with or without food. @stb its definitely not cheap. Vet Dermatol 2014;25:153 (abstract). Apoquel is not FDA approved to use twice daily longer than 14 days. And some can got a lower dose or a further spread out dose. Skip to Article Content; Skip to Article Information; Search within. A Magnawave-certified practitioner, Lucile also runs a small equine PEMF therapy business. Oclacitinib maleate is used twice daily for two weeks and then dropped to a maintenance dose of once daily. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. The efficacy of oclacitinib was also compared to that of other drugs such as prednisolone and cyclosporine. These animals require the opposite regimen. The mare luckily didnt have a lot of food allergies and eliminating flax wasnt a big deal. She added, "Studies show that omega-3 fatty acids help horses with equine asthma. Have you considered trying allergy testing? Apoquel can be administered with or without food. Hydroxyzine is usually given orally twice to three times daily in dogs, cats, horses and birds. Table of Contents hide Apoquel dosage for dogs chart Apoquel for Dogs Reviews: Does It Really Work? Definitely less than a horse lol but 1.5 16mg tabs a day is $$. Typically, a few sessions are required. Allergies primarily affect the immune, respiratory, and integumentary (skin) systems and, if unmanaged, can seriously impact an animals performance and well-being. 22. Several of their drugs are eligible. Oclacitinib is available in 3 different tablet sizes: 3.6, 5.4, and 16 mg. It's typically prescribed twice daily for up to 14 days and then once daily after that. Adverse events were reported in less than 5% of dogs, including urinary tract infection, vomiting, otitis, pyoderma, and diarrhea.9 A subsequent study concluded that there is no increased risk for urinary tract infections.10, The efficacy of oclacitinib was also compared to that of other drugs such as prednisolone and cyclosporine. My dog has been on apoquel for about 2 years. Before your vet administers immunotherapy, though, you must identify your horses respiratory and skin allergies. Posted by Lucile Vigouroux | May 4, 2022 | Article, Diseases and Conditions, Farm and Barn, Hives & Skin Allergies, Horse Care, Medications, Nutrition, Seasonal Care, Skin Problems. These can be severe and lead to a life-threatening, airway-blocking, whole-body reaction called anaphylaxis. This medication may be a very good option for minis, since the costs will be much lower. (https://www.zoetispetcare.com) I get $9 back for every 30 pills I order, it goes onto a Mastercard debit card that can only be used at a vets office but I spend plenty of money there. Many of these cytokines bind to cytokine receptors that have JAK enzymes associated with their cytoplasmic portion. Vet Dermatol 2015;26:297 (abstract). found a significant improvement in 76% of horses with skin allergies within one year of using allergen-desensitization serums. In atopic dermatitis, it is mainly mediated by a large group of proinflammatory and proallergic Th2 cytokines (e.g., interleukin [IL]-4, IL-5, IL-10, IL-13, IL-31). This product is a hand-held device that administers an anti-inflammatory mist into the horses nostril. Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. Apoquel is a prescription dog allergy medicine used for the control of itch associated with allergic dermatitis and control of atopic dermatitis in dogs 12 months and older. Vet Dermatol 2015;26(1):23-30, e7-8. Use of oclacitinib (Apoquel; Zoetis) for treatment of cutaneous mastocytosis in a cat. If your horse's test results (from a BAL or tracheal wash) show a certain cell type in the lungs, we may recommend trying Zyrtec!Clenbuterol: This is a bronchodilator that may be beneficial in treating some horses with Equine Asthma. The efficacy and safety of oclacitinib have been assessed in various studies. Orthobiologic Options for Treating Horses. Its anti-inflammatory and expectorant properties can soothe irritated lung tissues and help to expel mucus.Licorice root should not be fed to pregnant mares. Pet owners should visit ZoetisPetcare.com for product info, rewards and support. A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats. Pros and cons of oclacitinib therapy. Apoquel sorted the problem in a day but after doing some research after noticing her doing some chewing again Apoquel has some disturbing side effects as it suppresses the immune system. APQ-01043R3, halved to ensure that the ingredients are equally distributed. If you must give corticosteroids to an asthmatic horse, your veterinarian might prescribe them to be administered via an aerosol route through the nostril (rather than orally or via injection), which minimizes the amount that gets into the general circulation. In cats, this medication can cause excitement rather than sedation. 20. Dexamethasone: EZ Dose Micro Transdermal Gel, Dexamethasone: Twist-a-Dose Transdermal Gel, Discussion Guide for Pet Owners and Veterinarians, Medication Information for Pet and Horse Owners. These reports suggest the potential use of oclacitinib in other diseases; however, it cannot be stressed enough that the use of oclacitinib in these diseases is an off-label use. Pasture-associated equine asthma is most prevalent during the summer in the southeastern U.S. but has been reported worldwide. Licorice Roo t (Glycyrrhiza glabra) This sweet and soothing herb has been used medicinally for over 3,000 years. Many allergic reactions are evident as a mild case of transient hives. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. For more information, please see the full Prescribing Information. APOQUEL tablets may be administered with or without food. Having allergy tested 3 horses you can get a serum for some allergens but not all. Treatment may then be continued at the same dose given once a day. The dosage for dogs 10-14.9 lbs is of a 5.4 mg tablet twice daily. Although oclacitinib is licensed for use in dogs, it has been reported to be effective to treat pruritus in allergic diseases in other species, including cats. Dosage Chart Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. The drug is primarily used as a tranquilizer to calm anxious pets, especially dogs and horses, according to DailyMed. Each dosage is sold per tablet, in 20 count, or 100 count bottles. Alternatively, your veterinarian may be able to show you some techniques. I am not saying it is a cure all, but that and some generic Zyrtec make my mare a whole lot more comfortable. At that point, the treatment can be changed to oclacitinib. Gonzales AJ, Bowman JW, Fici GJ, et al. Therefore, in many of these cases, veterinarians use steroids sparingly, says Fultz, at lower doses than recommended, or they turn to non-steroidal medications. All dogs itch sometimes, but when you notice it happening more and more, it could be a sign of a medical condition. Allergies are generally managed based on the severity of clinical signs. This option has somewhat fewer risks than option 1, has a higher initial cost ($1,000 for the nebulizer mask), but a lower monthly cost- $20-$40/month. Aymeric E, Bensignor E. A case of presumed autoimmune subepidermal blistering dermatosis treated with oclacitinib. In this study, 70% of the study population receiving oclacitinib showed improvement in pruritus compared with 75% in a group receiving methylprednisolone.18 Based on this study, a higher dose with a longer induction period seems to be the key to successfully treating feline pruritus with oclacitinib. Apoquel is typically administered in tablet form at 0.4-0.6mg per kilo of body weight, or 0.18-0.27mg per pound of body weight, every 12 hours or twice a day. Apoquel reduces dog itch, and also decreases inflammation, redness, or swelling of the skinso your dog feels better as quickly as possible What is Apoquel Tablet? 8. Therefore, the recommended initial dosage for dogs 6.6-9.9 lbs is of a 3.6 mg tablet twice daily. actually treats degenerative joint disease (DJD), not just its clinical signs. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. It is an anti-inflammatory drug from the class of drugs known as Janus kinase (JAK) inhibitors. I had a cat on it years ago and it was $$$$ but it was the only thing that worked for her. Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. Now divide the 10,000 mg by the 500 mg in the concentration. Pollen and other plant-based aeroallergens are the source of their distress, and they fare much better inside, Many allergens can cause skin reactions. In the past 5 years, however, oclacitinib (Apoquel; ), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. Option 3 is using a nebulizer with dexamethasone and/or other drugs. Cosgrove SB, Cleaver DM, King VL, et al. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. In fact, in our. Left untreated, these conditions can not only cause discomfort but also lead to raw, broken skin that allows bacteria to invade and infect. It generally reduces itching very quickly within 24 hours and is felt to be as effective as corticosteroids. 3. Dawn M. Cleaver, DVM Associate Director, Regulatory Affairs Until recently, glucocorticoids (systemic and/or topical) and cyclosporine have been considered the most effective symptomatic treatment options to manage atopic dermatitis. Option 4 is an oral tablet called Apoquel. Designed by Elegant Themes | Powered by WordPress, You need to be logged in to fill out this form. The most common practical starting dosage for many cats is of the 5.4mg tablet, or 2.7mg. I paid $250 for 100 pills (thats 20 5-pill doses). Simpson AC, Schissler JR, Rosychuk RAW, et al. U.S. Food and Drug Administration Center for Veterinary Medicine 7500 Standish Place Rockville, MD 20855 www.fda.gov . 2022 Zoetis Services LLC. EHV Quarantine Released at Turf Paradise Racetrack, Six Simple Spring Safeguards for Senior Horses, Evaluating the Suspensory Ligament in Cutting Horses, Regular Dental Care Important in Horses Worldwide, Investigating Equine Cases of Toxicant Exposure, Podotrochlosis: Navicular is No Longer the End of the Road for Horses. Serious side effects include seizures, abnormal breathing, incoordination, muscle tremors, and coma. The efficacy and safety of oclacitinib have been assessed in various studies. What company did you use? Apoquel should not be used in breeding, pregnant, or lactating dogs. Oclacitinib was well tolerated in both studies. I spend $150 a month on my horse on apoquel. At that point, the treatment can be changed to oclacitinib. This is a new treatment option, and currently the tablets are not FDA approved for horses, only dogs. While efficacy was comparable to that observed in the previous studies, significant positive effects on the dogs quality of life were observed in >91.5% of cases after 630 days. Previcox is an FDA-approved non-steroidal anti-inflammatory (NSAID) prescription medication used in dogs to treat pain and inflammation associated with osteoarthritis and for the control of postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. A follow-up study assessed the long-term safety, efficacy, and quality of life of oclacitinib-treated dogs. Intradermal allergy testing is the gold standard for this and involves a veterinary dermatologist subcutaneously injecting very small quantities of potential allergens into a clipped patch of the horses neck. Collard WT, Hummel BD, Fielder AF, et al. Find out more. Despite its delayed effects, cyclosporine is still a popular drug to treat canine atopic dermatitis because in some cases it can be dosed every other day or even every third day after initial daily treatment. Do not use Apoquel in dogs less than 12 months of age or those with serious infections. On the topic of simple and economical allergy management, a readily accessible ingredient that helps many horses is flaxseed. Cochet Faivre N, Degorce-Rubiales F. Clinical eosinophilic popular dermatitis associated with histological eosinophilic granuloma rapidly responsive to oclacitinib in an adult Labrador retriever.